Synthesis Add 96g of acetic acid to the reaction vessel, add 32g of levulinic acid to dissolve under stirring, when completely dissolved, add 61.5g of acetic anhydride, then raise the temperature to 80 constant temperature reaction for 12 hours, the reaction is completed, in a vacuum of -0.09Mpa, the temperature of 80 below the distillation of acetic acid removal, reduce the temperature to 40 , add 160g of acetone, fully stirred and dispersed for 0.5 hours, reduced temperature to 5 below precipitation of crystals, and held between 0 ~ 5 for 2 hours, filtration and separation, wash the solid with acetone, in a vacuum -0.09 Mpa, dried at 80 , that is to obtain acetyl levulinic acid 36g finished product, yield 88.9%
Contraindicatii: Utilizare cu prudenta: femeile insarcinate sau care alapteaza ar trebui sa consulte un medic inainte de administrare, deoarece nu exista suficiente date privind siguranta in timpul sarcinii si alaptarii
GPx-1-encoded adenoviral vector attenuates dopaminergic impairments induced by methamphetamine in GPx-1 knockout mice through modulation of NF-kappaB transcription factor
Consuming foods rich in probiotics may enhance the absorption of vitamin B12, such as: Yoghurt Fermented vegetables 2