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10.1200/jco.2015.33.15_suppl.2512 66 HartleyJ

Tirzepatide is a dual agonist targeting GLP-1R and GIPR Retatrutide adds GCGR activation as a third receptor target

Consequently, further elucidation of Gln metabolic profiles and the utilisation of carriers, enzymes, or metabolites during aberrant energy metabolism as potential targets for cancer therapy would be expected to improve patient prognosis