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In nuclear, TFEB upregulates the mRNA expression of autophagy- and lysosome-related genes and simultaneously accelerates NCOA4-mediated ferritinophagy and lipophagy

Figure 3 Regarding iron homeostasis regulation, increased levels of Lactobacillus and Bifidobacterium species are correlated with reduced inflammation (184)

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Critically, it does not bind the GH receptor in the same way as full-length GH, so it does not elevate IGF-1 or affect glucose homeostasis