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Inverse relation of body weight and weight change with mortality and morbidity in patients with type 2 diabetes and cardiovascular co-morbidity: an analysis of the PROactive study population

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In SUSTAIN 6, subjects with T2D at high CV risk treated with semaglutide had a 26% lower risk of the primary composite outcome of first MACE (death from CV causes, nonfatal MI, or nonfatal stroke) vs those receiving placebo over 2 years (p = 0.02 for superiority [post hoc]) [12]

Seino Y, Terauchi Y, Osonoi T, Yabe D, Abe N, Nishida T, Zacho J, Kaneko S