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Supplementation with citrulline, but not ornithine or the nitric oxide donor sodium nitrite, restored the growth of the CR hi cell lines in these arginine-free conditions (Figure 6A), confirming that the mitochondrial component, rather than the cytosolic component of the urea cycle pathway, was unable to support continued proliferation in the absence of exogenous arginine

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In fact, as nicotine is distributed in the body much more slowly when vaping than when smoking tobacco, some vapers tend to pull considerably more on their individual vaper than they did on their tobacco cigarettes

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