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The benefits are cumulativemeaning the longer you use it, the more noticeable the effects

hazard ratio 0.71, 0.52 to 0.98) compared with the use of SGLT-2 inhibitors after a median follow-up time of 8.4 months

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The formation of this membrane associated enzyme complex results in the generation of superoxide anion which in turn is converted to hydrogen peroxide through the action of Cu-Zn superoxide dismutase (SOD1)