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Beyond glucose lowering, GLP-1 RAs have been shown to confer broad cardioprotective benefits including reductions in body weight, blood pressure, postprandial lipids, and inflammation [2]
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It is instructive that the 2021 EUGOGO guidelines include Se supplementation in the treatment regimen for mild GO, recommending a 6-month treatment with Se preparations for patients with mild GO of short duration to prevent the progression to more severe forms of GO (34)
These changes result from disrupted signaling between dermal papilla cells and matrix keratinocytes, decreased growth factor expression, and reduced proliferation in the follicular bulb [2, 27]
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