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It has demonstrated the ability to close complex fistulas (abnormal connections between organs) by simultaneously repairing internal mucosal defects and external skin tissue

This is comparable to bariatric surgery, which removes part of the stomach to help patients eat less and lose weight

Portfolio holdings that are valued using techniques other than market quotations, including "fair valued" assets or securities, may be subject to greater fluctuation in their valuations from one day to the next than if market quotations were used