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Niacin cures systemic NAD(+) deficiency and improves muscle performance in adult-onset mitochondrial myopathy

The startup quietly launched a program prescribing GLP-1s early in the year, BI reported in March

A pooled analysis of these two randomised-controlled trials demonstrated a placebo-adjusted reduction in OFF-time of 1 h from baseline to week 12 [143], and an open-label extension showed persistent improvement of MDS-UPDR part IV motor fluctuation subscore after 100 weeks of treatment [144, 145]