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Its less dependent on its mitochondria

Immune-deficient NOD-SCID-IL2RG-/- mice (NSI mice, GIBH) were used as recipients for in vivo transplantation experiments

The frequency of B12 injections varies based on individual needs: For deficiency correction: Injections may be administered more frequently, such as weekly or monthly, until levels normalize. For maintenance: Once adequate levels are achieved, monthly injections are typically recommended