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This is consistent with published evidence showing that Epigallocatechin-3-gallate suppresses pro-apoptotic gene expression at low doses while triggering pro-apoptotic profiles at high doses 47,48 , and that high GTE concentrations ( 15 mg/L) impair sperm quality parameters in multiple species 31

Fetal metabolism uses sulfation pathways that become saturated, shunting more drug to the toxic pathway

(j) NIR-II image-guided subcutaneous tumor resection

This reduction in GPx and GST activities would lead to a decrease in GSH synthesis, which would affect many essential metabolic pathways in which GSH is involved