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These include: Complete Blood Count (CBC) to check for better anemia Serum Vitamin B12 levels to make sure the dose is right Methylmalonic acid (MMA) and homocysteine levels to see how the body is reacting Reticulocyte count to see how the bone marrow is doing Clinical Improvement Markers We also watch for signs of improvement in how patients feel

Anaesthetic None required

Therefore, injection frequency is far more crucial than the dose

IM B12 injection is especially appropriate when oral supplementation has been inadequate, when absorption is compromised, or when neurological symptoms are present (Stabler, New England Journal of Medicine , 2013)