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Central GLP-1 binds to GLP-1 receptor (GLP-1R) to exert many important effects including modulation of energy balance, cardiovascular system, learning and memory, rewarding effect of food, and thermogenesis (Trapp and Cork, 2015)

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Regarding live-birth rate, the population analyzed in the present study is smaller than that assessed in the Cochrane meta-analysis, since we focused only on spontaneous pregnancies