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Androgen receptor modulation optimized for response-splice variant: a phase 3, randomized trial of galeterone versus enzalutamide in androgen receptor splice variant-7-expressing metastatic castration-resistant prostate cancer

In the published literature the combination is investigated for body-weight reduction and glycemic control , on the hypothesis that engaging the amylin and GLP-1 pathways together influences appetite and energy balance more than either agent does alone [3]

Schucht P, Raineteau O, Schwab OE, Fouad K