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Measurable weight loss often starts within 2 to 4 weeks, while more significant results typically become noticeable after 8 to 12 weeks of consistent treatment

References Moiz A, Filion KB, Tsoukas MA, Yu OH, Peters TM, Eisenberg MJ

While tirzepatide does not directly target these pathways, the metabolic improvements and weight reduction it facilitates may indirectly support healthier reproductive hormone profiles