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PCR data showed that 200 M H 2 O 2 treatment upregulated IL-1, MMP13, Collagen-X, Caspase3, and Caspase9 at mRNA level in chondrocytes, while metformin significantly attenuated these H 2 O 2 exposure induced increases (Fig

Both saline- and GHRP-6-treated groups exhibited significant body weight loss compared to healthy sentinel rats, indicating that GHRP-6 did not prevent the cachectic weight loss induced by Dox

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The frequency of treatments varies