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Nat Rev Cancer 13(5):299314 Cabrera J, Negrn G, Estvez F, Loro J, Reiter RJ, Quintana J (2010) Melatonin decreases cell proliferation and induces melanogenesis in human melanoma SK-MEL-1 cells

Trans-melanosomal transportation can be achieved through a membrane channel or diffusion, both of which seem to be lacking for GSH, a fact well established in previous research [20,21]

Moreover, LLB was found to downregulate NF-B, p-PI3K, and pAKT, while simultaneously upregulating IB expression, thereby providing renal protection against mesangial proliferative glomerulonephritis (MsPGN) in rat models (Zhao et al., 2019)

This review integrates molecular, developmental, and clinical evidence to highlight the role of iron dysregulation in ASD with a focus on iron imbalance at different stages of neurodevelopment