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When administered as a once-daily subcutaneous injection, Saxenda acts on several mechanisms to promote weight loss: Appetite suppression : It acts on areas of the brain that regulate appetite, helping patients feel fuller for longer periods Delayed gastric emptying : The medication slows the rate at which food leaves the stomach, contributing to prolonged satiety Improved glucose regulation : It enhances insulin secretion when blood glucose levels are elevated According to the Summary of Product Characteristics (SmPC), Saxenda is licensed for adults with a body mass index (BMI) of 30 kg/m or greater, or 27 kg/m or greater in the presence of weight-related comorbidities such as hypertension, type 2 diabetes, dyslipidaemia, or obstructive sleep apnoea

Nanomedicine 19, 75857603

doi: 10.1016/j.rbmo.2019.04.007 70 CacciottolaLDonnezJDolmansMM

Stress and Anxiety Chronic stress or even short-term anxiety about a specific problem can wreak havoc with your hormone balance, causing a missed or irregular period