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Adipocyte overexpression of PNPLA2 protected mice from weight gain on chow and HFD, decreased adipocyte size and increased FAO and turnover of TAG (238), supporting the cause for stimulating lipolysis therapeutically

Specifically, the research indicated that the fibrotic areas and the nodularity within the liver were decreased by an estimated 75% and more than 60%, respectively

The study found that while glutathione was elevated, other vital protective antioxidant enzymessuch as mitochondrial superoxide dismutase (SOD2)were severely depleted

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