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Previously, two octapeptides (both called lophyrotomin) and three heptapeptides (pergidin, 4-valinepergidin and dephosphorylated pergidin) were identified from three species in the family Pergidae and one in Argidae. Here, the hypothesis of widespread occurrence of these peptides among sawflies was tested by LC-MS analyses of single larvae from eight pergid and 28 argid species, plus nine outgroup species

Future research applications will likely expand to include investigation of senescence heterogeneity, tissue-specific senescent cell populations, and the development of personalized approaches to senolytic intervention based on individual senescent cell burden and characteristics

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